PAPERS - RESEARCH FRONT: 8

TITLE 1ST AUTHOR YEAR
Reactive microglia in Creutzfeldt-Jakob disease Muhleisen H 1995
Effectiveness of anthracycline against experimental prion disease in Syrian hamsters Tagliavini F 1997
Effect of flupirtine on bcl-2 and glutathione level in neuronal cells treated in vitro with the prion protein fragment (PrP 106-126) Perovic S 1997
The acute inflammatory response in CNS following injection of prion brain homogenate or normal brain homogenate Betmouni S 1999
Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins Combs CK 1999
Inflammatory response and retinal ganglion cell degeneration following intraocular injection of ME7 Russelakis-Carneiro M 1999
Upregulation of the genes encoding lysosomal hydrolases, a perforin-like protein, and peroxidases in the brains of mice affected with an experimental prion disease Kopacek J 2000
Cyclooxygenase-2 is highly expressed in microglial-like cells in a murine in model of prion disease Walsh DT 2000
Intracellular mechanisms mediating the neuronal death and astrogliosis induced by the prion protein fragment 106-126 Thellung S 2000
Absence of detectable IL-1 beta production in murine prion disease: A model of chronic neurodegeneration Walsh DT 2001
Fluoro-Jade and silver methods: application to the neuropathology of scrapie, a transmissible spongiform encephalopathy Ye XM 2001
Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease Combrinck MI 2002
Neuroprotective effect of flupirtine in prion disease Schroder HC 2002
Adult human microglia secrete cytokines when exposed to neurotoxic prion protein peptide: no intermediary role for prostaglandin E-2 Veerhuis R 2002
Transforming growth factor beta 1, the dominant cytokine in murine prion disease: influence on inflammatory cytokine synthesis and alteration of vascular extracellular matrix Cunningham C 2002
Atypical inflammation in the central nervous system in prion disease Perry VH 2002
Synthetic miniprion PrP106 Bonetto V 2002
Neuroinflammation in Alzheimer's disease and prion disease Eikelenboom P 2002
Apoptotic PC12 cells exposing phosphatidylserine promote the production of anti-inflammatory and neuroprotective molecules by microglial cells De Simone R 2003
Phenotypic variability in the brains of a family with a prion disease characterized by a 144-base pair insertion in the prion protein gene King A 2003
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic Florio T 2003
Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease Cunningham C 2003
Activation by prion peptide PrP106-126 induces a NF-kappa B-driven proinflammatory response in human monocyte-derived dendritic cells Bacot SM 2003
Ultrastructural changes in the optic nerves of rodents with experimental Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler-Scheinker disease (GSS) or scrapie Walis A 2003
Inducible cytokine gene expression in the brain in the ME7/CV mouse model of scrapie is highly restricted, is at a strikingly low level relative to the degree of gliosis and occurs only late in disease Brown AR 2003
Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein Salmona M 2003
Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E-2 synthesis Ajmone-Cat MA 2003
Enhanced detection and retrograde axonal transport of PrPc in peripheral nerve Moya KL 2004
Complement activation in human prion disease Kovacs GG 2004
Atypical anti inflammatory activation of microglia induced by apoptotic neurons - Possible role of phosphatidylserine-phosphatidylserine receptor interaction De Simone R 2004
Squalestatin cures prion-infected neurons and protects against prion neurotoxicity Bate C 2004
Neuropil and neuronal changes in hippocampal NADPH-diaphorase histochemistry in the ME7 model of murine prion disease Picanco-Diniz CW 2004
Role of interleukin-1 in prion disease-associated astrocyte activation Schultz J 2004
Identification of distinct N-terminal truncated forms of prion protein in different Creutzfeldt-Jakob disease subtypes Zanusso G 2004
Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology Xiang W 2004
Gene expression profiling of scrapie-infected brain tissue Riemer C 2004
Role of glycosylphosphatidylinositols in the activation of phospholipase A(2) and the neurotoxicity of prions Bate C 2004
Accelerated prion disease in the absence of interleukin-10 Thackray AM 2004
The expression of RANTES and chemokine receptors in the brains of scrapie-infected mice Lee HP 2005
Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease Chiesa R 2005
Hippocampal scrapie infection impairs operant DRL performance in mice Deacon RMJ 2005
Complement protein C1q recognizes a conformationally modified form of the prion protein Blanquet-Grossard F 2005
Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation Minghetti L 2005
Comparison of inflammatory and acute-phase responses in the brain and peripheral organs of the ME7 model of prion disease Cunningham C 2005
Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q Veerhuis R 2005