PAPERS - RESEARCH FRONT: 6
TITLE	1ST AUTHOR	YEAR
Consequences of manganese replacement of copper for prion protein function and proteinase resistance	Brown DR	2000
Functional and structural differences between the prion protein from two alleles prnp(a) and prnp(b) of mouse	Brown DR	2000
Evidence for oxidative stress in experimental prion disease	Guentchev M	2000
Breakthroughs and views - Prion disease: A loss of antioxidant function?	Wong BS	2000
PrPSc-like prion protein peptide inhibits the function of cellular prion protein	Brown DR	2000
The structural and spectroscopic basis for modelling prion protein interactions	Warwicker J	2001
Prion and prejudice: normal protein and the synapse	Brown DR	2001
Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region	Sumudhu W	2001
Copper and prion disease	Brown DR	2001
Aberrant metal binding by prion protein in human prion disease	Wong BS	2001
A Yin-Yang role for metals in prion disease	Wong BS	2001
Prion diseases: copper deficiency states associated with impaired nitrogen monoxide or carbon monoxide transduction and translocation	Sorenson JRJ	2001
Oxidative stress and the prion protein in transmissible spongiform encephalopathies	Milhavet O	2002
Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration	Mallucci GR	2002
Metal imbalance and compromised antioxidant function are early changes in prion disease	Thackray AM	2002
Oxidative damage to nucleic acids in human prion disease	Guentchev M	2002
Tethering the N-terminus of the prion protein compromises the cellular response to oxidative stress	Zeng FN	2003
Copper binding to the octarepeats of the prion protein - Affinity, specificity, folding, and cooperativity: Insights from circular dichroism	Garnett AP	2003
Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231	Turubull S	2003
The prion protein and neuronal zinc homeostasis	Watt NT	2003
Impairment of superoxide dismutase activation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line	Sakudo A	2003
No superoxide dismutase activity of cellular prion protein in vivo	Hutter G	2003
Prion protein expression modulates neuronal copper content	Brown DR	2003
Copper chelation delays the onset of prion disease	Sigurdsson EM	2003
Copper binding to PrPC may inhibit prion disease propagation	Hijazi N	2003
Metallic prions	Brown DR	2004
Copper induces increased beta-sheet content in the scrapie-susceptible ovine prion protein Prp(VRQ) compared with the resistant allelic variant Prp(ARR)	Wong E	2004
Preferential Cu2+ coordination by His(96) and His(111) induces beta-sheet formation in the unstructured amyloidogenic region of the prion protein	Jones CE	2004
Effect of metal ions on de novo aggregation of full-length prion protein	Giese A	2004
Octapeptide repeat region and N-terminal half of hydrophobic region of prion protein (PrP) mediate PrP-dependent activation of superoxide dismutase	Sakudo A	2005
Effect of transition metals (Mn, Cu, Fe) and deoxycholic acid (DA) on the conversion of PrPC to PrPres	Kim NH	2005
PrP cooperates with STI1 to regulate SOD activity in PrP-deficient neuronal cell line	Sakudo A	2005
Copper(II) inhibits in vitro conversion of prion protein into amyloid fibrils	Bocharova OV	2005