PAPERS - RESEARCH FRONT: 10

TITLE 1ST AUTHOR YEAR
Immunodiagnosis of prion disease Kascsak RJ 1997
Species barriers in a model for specific prion protein dimerisation Warwicker J 1997
Autocatalytic processes in cooperative mechanisms of prion diseases Laurent M 1997
Hypothesis: the meeting place model for prion disease Norris V 1997
Molecular pathogenesis of prion diseases Kretzschmar HA 1999
Strain-specific prion-protein conformation determined by metal ions Wadsworth JDF 1999
Alzheimer's and prion disease as disorders of protein conformation: implications for the design of novel therapeutic approaches Soto C 1999
The use of monoclonal antibodies in human prion disease Bodemer W 1999
Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein Wopfner F 1999
Proteasomal degradation and N-terminal protease resistance of the codon 145 mutant prion protein Zanusso G 1999
The kinetics of proteinase K digestion of linear prion polymers Masel J 1999
Glycosylation differences between the normal and pathogenic prion protein isoforms Rudd PM 1999
Prion protein glycosylation is sensitive to redox change Capellari S 1999
Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides Soto C 2000
Shortest known prion protein allele in highly BSE-susceptible lemurs Gilch S 2000
Susceptibility of the prion protein to enzymic phosphorylation Negro A 2000
Creutzfeldt-Jakob disease with a novel four extra-repeat insertional mutation in the PrP gene Rossi G 2000
Differential expression of metallothioneins in human prion diseases Kawashima T 2000
Conformational variability of the synthetic peptide 129-141 of the mouse prion protein Prevost M 2000
Amyloidgenicity and neurotoxicity of peptides corresponding to the helical regions of PrPC Thompson A 2000
Designing drugs to stop the formation of prion aggregates and other amyloids Masel J 2000
A simple kinetic model to describe the progression of prion disease Vitagliano V 2001
The measured level of prion infectivity varies in a predictable way according to the aggregation state of the infectious agent Masel J 2001
Increased expression of the normal cellular isoform of prion protein in inclusion-body myositis, inflammatory myopathies and denervation atrophy Zanusso G 2001
Absence of protease-resistant prion protein in the cerebrospinal fluid of Creutzfeldt-Jakob disease Wong BS 2001
Scrapie strains maintain biological phenotypes on propagation in a cell line in culture Birkett CR 2001
Intracellular re-routing of prion protein prevents propagation of PrPSc and delays onset of prion disease Gilch S 2001
A protease-resistant prion protein isoform is present in urine of animals and humans affected with prion diseases Shaked GM 2001
Mutation of the PRNP gene at codon 211 in familial Creutzfeldt-Jakob disease Ladogana A 2001
Prion diseases: Dynamics of the infection and properties of the bistable transition Kellershohn N 2001
Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation Ma JY 2001
Inherited prion disease caused by the V210I mutation - Transmission to transgenic mice Mastrianni JA 2001
Prion disease: Close encounters of the cellular kind Hooper NM 2002
Analysis of the prion protein in primates reveals a new polymorphism in codon 226 (Y226F) Glatzel M 2002
Lipid peroxidation in neurodegeneration: new insights into Alzheimer's disease Arlt S 2002
Increased lipid peroxidation in cerebrospinal fluid and plasma from patients with Creutzfeldt-Jakob disease Arlt S 2002
Expression patterns of antioxidant proteins in brains of patients with sporadic Creutzfeldt-Jacob disease Krapfenbauer K 2002
Intercellular transfer of the cellular prion protein Liu T 2002
Overexpressed protein disulfide isornerase in brains of patients with sporadic Creutzfeldt-Jakob disease Yoo BC 2002
Making yeast tremble - Yeast models as tools to study neurodegenerative disorders Sherman MY 2003
Copper reduction by copper binding proteins and its relation to neurodegenerative diseases Opazo C 2003
Are humans getting 'mad-cow disease' from eating beef, or something else? Concepcion GP 2003
Cooperative binding of dominant-negative prion protein to kringle domains Ryou C 2003
Prion protein trafficking and the development of neurodegeneration Hegde RS 2003
Theoretical modeling of prion disease incubation Kulkarni RV 2003
RNA molecules stimulate prion protein conversion Deleault NR 2003
Humanized knock-in mice expressing chimeric prion protein showed varied susceptibility to different human prions Taguchi Y 2003
Prion disease and Alzheimer's disease: pathogenic overlap Castellani RJ 2004
Quantitative analysis of prion-protein degradation by constitutive and immuno-20S proteasomes indicates differences correlated with disease susceptibility Tenzer S 2004
The C-terminal globular domain of the prion protein is necessary and sufficient for import into the endoplasmic reticulum Heske J 2004
Autocatalytic conversion of recombinant prion proteins displays a species barrier Baskakov IV 2004
In vitro prion protein conversion in detergent-solubilized membranes Nishina K 2004
Recognition of lumenal prion protein aggregates by post-ER quality control mechanisms is mediated by the preoctarepeat region of PrP Gilch S 2004
Prion protein conversion in vitro Supattapone S 2004
The neurodegeneration sequence in prion diseases: Evidence from functional, morphological and ultrastructural studies of the GABAergic system Bouzamondo-Bernstein E 2004
RNA mutagenesis and sporadic prion diseases Garcion E 2004
Discovering the mechanisms of neurodegeneration in prion diseases DeArmond SJ 2004
Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: Implications for species barrier in prion uptake from the intestine Mishra RS 2004
Oxidation of methionine residues in the prion protein by hydrogen peroxide Requena JR 2004
Biochemical fingerprints of prion infection: Accumulations of aberrant full-length and N-terminally truncated PrP species are common features in mouse prion disease Pan T 2005
Calpain and other cytosolic proteases can contribute to the degradation of retro-translocated prion protein in the cytosol Wang XH 2005
Notch-1 activation and dendritic atrophy in prion disease Ishikura N 2005
Prion-associated increases in Src-family kinases Nixon RR 2005
Quantifying the parameters of Prusiner's heterodimer model for prion replication Li ZR 2005
In vitro conversion of mammalian prion protein into amyloid fibrils displays unusual features Baskakov IV 2005
Diagnosis of human prion disease Safar JG 2005
Characterization of the F198S prion protein mutation: Enhanced glycosylation and defective refolding Zaidi SIA 2005
From microbes to prions: The final proof of the prion hypothesis Zou WQ 2005
Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPSc from sporadic Creutzfeldt-Jakob disease Bocharova OV 2005
Biological and biochemical characteristics of prion strains conserved in persistently infected cell cultures Arima K 2005
Cell line dependent RNA expression profiles of prion-infected mouse neuronal cells Greenwood AD 2005
Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells Fernaeus S 2005